| 30 mei 2027 | Real Betis – Atlético Madrid | ––– | |
| 9 mei 2027 | Real Betis – Espanyol | ––– | |
| 2 mei 2027 | Real Betis – Valencia | ––– | |
| 18 apr 2027 | Real Betis – Athletic Bilbao | ––– | |
| 4 apr 2027 | Real Betis – Celta de Vigo | ––– | |
| 14 mrt 2027 | Real Betis – Levante FC | ––– | |
| 28 feb 2027 | Real Betis – Villarreal CF | ––– | |
| 7 feb 2027 | Real Betis – Sevilla FC | ––– | |
| 31 jan 2027 | Real Betis – Elche CF | ––– | |
| 17 jan 2027 | Real Betis – Deportivo La Coruña | ––– | |
| 3 jan 2027 | Real Betis – Deportivo Alavés | ––– | |
| 13 dec 2026 | Real Betis – Racing Santander | ––– | |
| 29 nov 2026 | Real Betis – Rayo Vallecano | ––– | |
| 1 nov 2026 | Real Betis – Málaga CF | ––– | |
| 18 okt 2026 | Real Betis – FC Barcelona | ––– | |
| 11 okt 2026 | Real Betis – Osasuna | ––– | |
| 16 sep 2026 | Real Betis – Getafe CF | ––– | |
| 4 sep 2026 | Real Betis – Real Madrid CF | ––– | |
| 21 aug 2026 | Real Betis – Real Sociedad | 1–0 | |
| 23 mei 2026 | Real Betis – Levante FC | 2–1 | |
| 12 mei 2026 | Real Betis – Elche CF | 2–1 | |
| 3 mei 2026 | Real Betis – Oviedo | 3–0 | |
| 24 apr 2026 | Real Betis – Real Madrid CF | 1–1 | |
| 4 apr 2026 | Real Betis – Espanol | 0–0 | |
| 15 mrt 2026 | Real Betis – Celta de Vigo | 1–1 | |
| 1 mrt 2026 | Real Betis – Sevilla FC | 2–2 | |
| 21 feb 2026 | Real Betis – Rayo Vallecano | 1–1 | |
| 1 feb 2026 | Real Betis – Valencia | 2–1 | |
| 17 jan 2026 | Real Betis – Villarreal CF | 2–0 | |
| 21 dec 2025 | Real Betis – Getafe CF | 4–0 | |